Effect of fibrinogen concentrate on clot strength in trauma: preliminary results of an in vitro study
نویسندگان
چکیده
Background Fibrinogen supplementation in trauma has been suggested in order to restore or improve haemostatic competence; this could possibly reduce or replace the need for transfusions in case of bleeding. Results from functional haemostatic assays indicate that lowered clot strength is associated with a risk for massive transfusions [1]. The optimal fibrinogen concentration or indications for supplementation in trauma patients have not been established [2].
منابع مشابه
Free oscillation rheometry monitoring of haemodilution and hypothermia and correction with fibrinogen and factor XIII concentrates
BACKGROUND Haemodilution and hypothermia induce coagulopathy separately, but their combined effect on coagulation has not been widely studied. Fibrinogen concentrate can correct dilutional coagulopathy and has an additional effect when combined with factor XIII concentrate. However, their effect on dilutional coagulopathy concomitant with hypothermia has not been studied previously. Free oscill...
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عنوان ژورنال:
دوره 20 شماره
صفحات -
تاریخ انتشار 2012